HDAC6 Deacetylates and Ubiquitinates MSH2 to Maintain Proper Levels of MutSα

MutS protein homolog 2 (MSH2) is a key DNA mismatch repair protein. It forms the MSH2-MSH6 (MutSα) and MSH2-MSH3 (MutSβ) heterodimers, which help to ensure genomic integrity. MutSα not only recognizes and repairs mismatched nucleotides but also recognizes DNA adducts induced by DNA-damaging agents,...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Zhang, Mu, Xiang, Shengyan, Joo, Heui-Yun, Wang, Lei, Williams, Kendra A., Liu, Wei, Hu, Chen, Tong, Dan, Haakenson, Joshua, Wang, Chuangui, Zhang, Shengping, Pavlovicz, Ryan E., Jones, Amanda, Schmidt, Kristina H., Tang, Jinfu, Dong, Huiqin, Shan, Bin, Fang, Bin, Radhakrishnan, Rangasudhagar, Glazer, Peter M., Matthias, Patrick, Koomen, John, Seto, Edward, Bepler, Gerold, Nicosia, Santo V., Chen, Jiandong, Li, Chenglong, Gu, Liya, Li, Guo-Min, Bai, Wenlong, Wang, Hengbin, Zhang, Xiaohong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188514/
https://ncbi.nlm.nih.gov/pubmed/24882211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.04.028
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items