Structures of human constitutive nitric oxide synthases

Mammals produce three isoforms of nitric oxide synthase (NOS): neuronal NOS (nNOS), inducible NOS (iNOS) and endothelial NOS (eNOS). The overproduction of NO by nNOS is associated with a number of neurodegenerative disorders; therefore, a desirable therapeutic goal is the design of drugs that target...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Huiying, Jamal, Joumana, Plaza, Carla, Pineda, Stephanie Hai, Chreifi, Georges, Jing, Qing, Cinelli, Maris A., Silverman, Richard B., Poulos, Thomas L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: International Union of Crystallography 2014
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188008/
https://ncbi.nlm.nih.gov/pubmed/25286850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714017064
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