Nitrile In The Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors

Antzeko izenburuak

• Simplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition
  nork: Cinelli, Maris A., et al.
  Argitaratua: (2014)
• First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate
  nork: Cinelli, Maris A., et al.
  Argitaratua: (2020)
• Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors
  nork: Pensa, Anthony V., et al.
  Argitaratua: (2017)
• Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase
  nork: Cinelli, Maris A., et al.
  Argitaratua: (2015)
• Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase
  nork: Cinelli, Maris A., et al.
  Argitaratua: (2016)