Effect of Coadministered Fat on the Tolerability, Safety, and Pharmacokinetic Properties of Dihydroartemisinin-Piperaquine in Papua New Guinean Children with Uncomplicated Malaria

Coadministration of dihydroartemisinin-piperaquine (DHA-PQ) with fat may improve bioavailability and antimalarial efficacy, but it might also increase toxicity. There have been no studies of these potential effects in the pediatric age group. The tolerability, safety, efficacy, and pharmacokinetics...

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Detaylı Bibliyografya
Asıl Yazarlar: Moore, B. R., Benjamin, J. M., Salman, S., Griffin, S., Ginny, E., Page-Sharp, M., Robinson, L. J., Siba, P., Batty, K. T., Mueller, I., Davis, T. M. E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2014
Konular:
Clinical Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187992/
https://ncbi.nlm.nih.gov/pubmed/25049242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03314-14
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