Pharmacokinetics and Efficacy of Piperaquine and Chloroquine in Melanesian Children with Uncomplicated Malaria

The disposition of chloroquine (CQ) and the related 4-aminoquinoline, piperaquine (PQ), were compared in Papua New Guinean children with uncomplicated malaria. Twenty-two children were randomized to 3 days of PQ phosphate at 20 mg/kg/day (12 mg of PQ base/kg/day) coformulated with dihydroartemisinin...

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Detalhes bibliográficos
Main Authors: Karunajeewa, Harin A., Ilett, Kenneth F., Mueller, Ivo, Siba, Peter, Law, Irwin, Page-Sharp, Madhu, Lin, Enmoore, Lammey, Jovitha, Batty, Kevin T., Davis, Timothy M. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223898/
https://ncbi.nlm.nih.gov/pubmed/17967917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00555-07
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