Population Pharmacokinetics of Artemether, Lumefantrine, and Their Respective Metabolites in Papua New Guinean Children with Uncomplicated Malaria

There are sparse published data relating to the pharmacokinetic properties of artemether, lumefantrine, and their active metabolites in children, especially desbutyl-lumefantrine. We studied 13 Papua New Guinean children aged 5 to 10 years with uncomplicated malaria who received the six recommended...

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Main Authors: Salman, Sam, Page-Sharp, Madhu, Griffin, Susan, Kose, Kaye, Siba, Peter M., Ilett, Kenneth F., Mueller, Ivo, Davis, Timothy M. E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194999/
https://ncbi.nlm.nih.gov/pubmed/21876056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05136-11
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