Population Pharmacokinetics of Artemether, Lumefantrine, and Their Respective Metabolites in Papua New Guinean Children with Uncomplicated Malaria

There are sparse published data relating to the pharmacokinetic properties of artemether, lumefantrine, and their active metabolites in children, especially desbutyl-lumefantrine. We studied 13 Papua New Guinean children aged 5 to 10 years with uncomplicated malaria who received the six recommended...

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Bibliographic Details
Main Authors: Salman, Sam, Page-Sharp, Madhu, Griffin, Susan, Kose, Kaye, Siba, Peter M., Ilett, Kenneth F., Mueller, Ivo, Davis, Timothy M. E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194999/
https://ncbi.nlm.nih.gov/pubmed/21876056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05136-11
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