Population Pharmacokinetics, Tolerability, and Safety of Dihydroartemisinin-Piperaquine and Sulfadoxine-Pyrimethamine-Piperaquine in Pregnant and Nonpregnant Papua New Guinean Women

The tolerability, safety, and disposition of dihydroartemisinin (DHA) and piperaquine (PQ) were assessed in 32 pregnant (second/third trimester) and 33 nonpregnant Papua New Guinean women randomized to adult treatment courses of DHA-PQ (three daily doses) or sulfadoxine-pyrimethamine (SP)-PQ (three...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Benjamin, John M., Moore, Brioni R., Salman, Sam, Page-Sharp, Madhu, Tawat, Somoyang, Yadi, Gumal, Lorry, Lina, Siba, Peter M., Batty, Kevin T., Robinson, Leanne J., Mueller, Ivo, Davis, Timothy M. E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468729/
https://ncbi.nlm.nih.gov/pubmed/25963981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00326-15
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