Effect of Coadministered Fat on the Tolerability, Safety, and Pharmacokinetic Properties of Dihydroartemisinin-Piperaquine in Papua New Guinean Children with Uncomplicated Malaria

Coadministration of dihydroartemisinin-piperaquine (DHA-PQ) with fat may improve bioavailability and antimalarial efficacy, but it might also increase toxicity. There have been no studies of these potential effects in the pediatric age group. The tolerability, safety, efficacy, and pharmacokinetics...

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Detalhes bibliográficos
Main Authors: Moore, B. R., Benjamin, J. M., Salman, S., Griffin, S., Ginny, E., Page-Sharp, M., Robinson, L. J., Siba, P., Batty, K. T., Mueller, I., Davis, T. M. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187992/
https://ncbi.nlm.nih.gov/pubmed/25049242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03314-14
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