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Obesity‐dependent dysregulation of glucose homeostasis in kinase suppressor of ras 2(−/−) mice
Disruption of KSR2 in humans and mice decreases metabolic rate and induces obesity, coincident with dysregulation of glucose homeostasis. Relative to wild‐type mice, ksr2(−/−) mice are small prior to weaning with normal glucose tolerance at 6 weeks of age, but demonstrate excess adiposity by 9 weeks...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Wiley Periodicals, Inc.
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187555/ https://ncbi.nlm.nih.gov/pubmed/24997067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12053 |
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