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Kinase Suppressor of Ras 2 (KSR2) Regulates Tumor Cell Transformation via AMPK

Kinase suppressor of Ras 1 (KSR1) and KSR2 are scaffolds that promote extracellular signal-regulated kinase (ERK) signaling but have dramatically different physiological functions. KSR2(−/−) mice show marked deficits in energy expenditure that cause obesity. In contrast, KSR1 disruption has inconseq...

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Detalhes bibliográficos
Main Authors: Fernandez, Mario R., Henry, MaLinda D., Lewis, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430199/
https://ncbi.nlm.nih.gov/pubmed/22801368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06754-11
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