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Kinase Suppressor of Ras 2 (KSR2) Regulates Tumor Cell Transformation via AMPK
Kinase suppressor of Ras 1 (KSR1) and KSR2 are scaffolds that promote extracellular signal-regulated kinase (ERK) signaling but have dramatically different physiological functions. KSR2(−/−) mice show marked deficits in energy expenditure that cause obesity. In contrast, KSR1 disruption has inconseq...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430199/ https://ncbi.nlm.nih.gov/pubmed/22801368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06754-11 |
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