Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma

Myc oncogenic transcription factors (c-Myc, N-Myc, and L-Myc) coordinate the control of cell growth, division, and metabolism. In cancer, Myc overexpression is often associated with aggressive disease, which is in part due to the destruction of select targets by the ubiquitin-proteasome system (eg,...

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Dades bibliogràfiques
Autors principals: Hoellein, Alexander, Fallahi, Mohammad, Schoeffmann, Stephanie, Steidle, Sabine, Schaub, Franz X., Rudelius, Martina, Laitinen, Iina, Nilsson, Lisa, Goga, Andrei, Peschel, Christian, Nilsson, Jonas A., Cleveland, John L., Keller, Ulrich
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186537/
https://ncbi.nlm.nih.gov/pubmed/25143484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-584524
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