Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma

Myc oncogenic transcription factors (c-Myc, N-Myc, and L-Myc) coordinate the control of cell growth, division, and metabolism. In cancer, Myc overexpression is often associated with aggressive disease, which is in part due to the destruction of select targets by the ubiquitin-proteasome system (eg,...

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Detalhes bibliográficos
Main Authors: Hoellein, Alexander, Fallahi, Mohammad, Schoeffmann, Stephanie, Steidle, Sabine, Schaub, Franz X., Rudelius, Martina, Laitinen, Iina, Nilsson, Lisa, Goga, Andrei, Peschel, Christian, Nilsson, Jonas A., Cleveland, John L., Keller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186537/
https://ncbi.nlm.nih.gov/pubmed/25143484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-584524
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