Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma

Myc oncogenic transcription factors (c-Myc, N-Myc, and L-Myc) coordinate the control of cell growth, division, and metabolism. In cancer, Myc overexpression is often associated with aggressive disease, which is in part due to the destruction of select targets by the ubiquitin-proteasome system (eg,...

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Библиографические подробности
Главные авторы: Hoellein, Alexander, Fallahi, Mohammad, Schoeffmann, Stephanie, Steidle, Sabine, Schaub, Franz X., Rudelius, Martina, Laitinen, Iina, Nilsson, Lisa, Goga, Andrei, Peschel, Christian, Nilsson, Jonas A., Cleveland, John L., Keller, Ulrich
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2014
Предметы:
Lymphoid Neoplasia
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186537/
https://ncbi.nlm.nih.gov/pubmed/25143484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-584524
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