P01.16 MICROGLIA/MACROPHAGES AS CELLULAR TARGET OF NOVEL CXCR4 ANTAGONIST IN A GLIOMA MODEL

BACKGROUND: The CXCL12/CXCR4 signaling pathway has been recently described regulating proliferation, metastasis and angiogenesis in several solid tumors, including brain malignances and modulate the cross-talk between tumor and microenvironment. In gliomas recent studies demonstrated that tumor cell...

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Hauptverfasser: Mercurio, L., Ajmone-Cat, M., Cecchetti, S., Ricci, A., Portella, L., Amodeo, P., Vitale, R., Scala, S., Minghetti, L., Carpinelli, G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Poster Presentations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185449/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.109
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