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P01.17 ROLE OF PHOSPHATYDILCHOLINE-SPECIFIC PHOSPHOLIPASE C IN MODULATION OF CXCL12/CXCR4 AXIS IN A HUMAN GLIOMA CELL LINE

BACKGROUND: The CXCR4 chemokine receptor and its ligand CXCL12 are one of the most well studied chemokine systems in tumor biology. In gliomas CXCL12/CXCR4 axis regulates multiple mechanisms that sustain tumor growth as migration, proliferation, angiogenesis and is emerging as a novel biologically r...

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Main Authors: Mercurio, L., Ricci, A., Cecchetti, S., Pacella, A., Podo, F., Iorio, E., Carpinelli, G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185451/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.110
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