Загрузка...
Multiple Propofol-binding Sites in a γ-Aminobutyric Acid Type A Receptor (GABA(A)R) Identified Using a Photoreactive Propofol Analog
Propofol acts as a positive allosteric modulator of γ-aminobutyric acid type A receptors (GABA(A)Rs), an interaction necessary for its anesthetic potency in vivo as a general anesthetic. Identifying the location of propofol-binding sites is necessary to understand its mechanism of GABA(A)R modulatio...
Сохранить в:
| Главные авторы: | , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2014
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183786/ https://ncbi.nlm.nih.gov/pubmed/25086038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.581728 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|