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Synthesis of a des-B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core
[Image: see text] A convergent synthesis of a des-B-ring bryostatin analogue is described. This analogue was found to undergo an unexpected ring expansion of the bryolactone core to generate the corresponding 21-membered macrocycle. The parent analogue and the ring-expanded product both displayed na...
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Autori principali: | , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Chemical
Society
2014
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Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183620/ https://ncbi.nlm.nih.gov/pubmed/25207434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5078188 |
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