Caricamento...

Synthesis of a des-B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core

[Image: see text] A convergent synthesis of a des-B-ring bryostatin analogue is described. This analogue was found to undergo an unexpected ring expansion of the bryolactone core to generate the corresponding 21-membered macrocycle. The parent analogue and the ring-expanded product both displayed na...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kraft, Matthew B., Poudel, Yam B., Kedei, Noemi, Lewin, Nancy E., Peach, Megan L., Blumberg, Peter M., Keck, Gary E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183620/
https://ncbi.nlm.nih.gov/pubmed/25207434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5078188
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !