Synthesis of a des-B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core

Gelijkaardige items

• Substitution on the A-Ring Confers to Bryopyran Analogues the Unique Biological Activity Characteristic of Bryostatins and Distinct From That of the Phorbol Esters
  door: Keck, Gary E., et al.
  Gepubliceerd in: (2009)
• Synthesis and Biological Evaluation of Several Bryostatin Analogues Bearing a Diacylglycerol Lactone C-Ring
  door: Baumann, David O., et al.
  Gepubliceerd in: (2016)
• Molecular Modeling, Total Synthesis, and Biological Evaluations of C9-Deoxy Bryostatin 1
  door: Keck, Gary E., et al.
  Gepubliceerd in: (2010)
• Synthesis of seco-B-Ring Bryostatin Analogue WN-1 via C–C Bond-Forming Hydrogenation: Critical Contribution of the B-Ring in Determining Bryostatin-like and Phorbol 12-Myristate 13-Acetate-like Properties
  door: Andrews, Ian P., et al.
  Gepubliceerd in: (2014)
• The Bryostatin 1 A-Ring Acetate is Not the Critical Determinant for Antagonism of Phorbol Ester-Induced Biological Responses
  door: Keck, Gary E., et al.
  Gepubliceerd in: (2009)