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Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal
Wnt/β-catenin signalling has a variety of roles in regulating stem cell fates. Its specific role in mouse epiblast stem cell self-renewal, however, remains poorly understood. Here we show that Wnt/β-catenin functions in both self-renewal and differentiation in mouse epiblast stem cells. Stabilizatio...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183150/ https://ncbi.nlm.nih.gov/pubmed/23985566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3403 |
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