Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal

Wnt/β-catenin signalling has a variety of roles in regulating stem cell fates. Its specific role in mouse epiblast stem cell self-renewal, however, remains poorly understood. Here we show that Wnt/β-catenin functions in both self-renewal and differentiation in mouse epiblast stem cells. Stabilizatio...

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Bibliografiske detaljer
Main Authors: Kim, Hoon, Wu, Jun, Ye, Shoudong, Tai, Chih-I, Zhou, Xingliang, Yan, Hexin, Li, Ping, Pera, Martin, Ying, Qi-Long
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183150/
https://ncbi.nlm.nih.gov/pubmed/23985566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3403
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