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ENaC activity and expression is decreased in the lungs of protein kinase C-α knockout mice
We used a PKC-α knockout model to investigate the regulation of alveolar epithelial Na(+) channels (ENaC) by PKC. Primary alveolar type II (ATII) cells were subjected to cell-attached patch clamp. In the absence of PKC-α, the open probability (P(o)) of ENaC was decreased by half compared with wild-t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4182288/ https://ncbi.nlm.nih.gov/pubmed/25015976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00040.2014 |
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