Alveolar nonselective channels are ASIC1a/α-ENaC channels and contribute to AFC

A thin fluid layer in alveoli is normal and results from a balance of fluid entry and fluid uptake by transepithelial salt and water reabsorption. Conventional wisdom suggests the reabsorption is via epithelial Na(+) channels (ENaC), but if all Na(+) reabsorption were via ENaC, then amiloride, an EN...

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Bibliographic Details
Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Trac, Phi T., Thai, Tiffany L., Linck, Valerie, Zou, Li, Greenlee, Megan, Yue, Qiang, Al-Khalili, Otor, Alli, Abdel A., Eaton, Amity F., Eaton, Douglas C.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495939/
https://ncbi.nlm.nih.gov/pubmed/28283476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00379.2016
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