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ENaC activity is regulated by calpain-2 proteolysis of MARCKS proteins

We previously demonstrated a role for the myristoylated alanine-rich C kinase substrate (MARCKS) to serve as an adaptor protein in the anionic phospholipid phosphate-dependent regulation of the epithelial sodium channel (ENaC). Both MARCKS and ENaC are regulated by proteolysis. Calpains are a family...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Montgomery, Darrice S., Yu, Ling, Ghazi, Zinah M., Thai, Tiffany L., Al-Khalili, Otor, Ma, He-Ping, Eaton, Douglas C., Alli, Abdel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538800/
https://ncbi.nlm.nih.gov/pubmed/28468944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00244.2016
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