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Calmodulin and CaMKII modulate ENaC activity by regulating the association of MARCKS and the cytoskeleton with the apical membrane
Phosphatidylinositol bisphosphate (PIP(2)) regulates epithelial sodium channel (ENaC) open probability. In turn, myristoylated alanine-rich C kinase substrate (MARCKS) protein or MARCKS-like protein 1 (MLP-1) at the plasma membrane regulates the delivery of PIP(2) to ENaC. MARCKS and MLP-1 are regul...
Enregistré dans:
| Publié dans: | Am J Physiol Renal Physiol |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556887/ https://ncbi.nlm.nih.gov/pubmed/26136560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00631.2014 |
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