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Biphasic regulation of ENaC by TGF-α and EGF in renal epithelial cells
The epithelial sodium channel (ENaC) is regulated by epidermal growth factor (EGF). We investigate whether ENaC is regulated by another EGF receptor (EGFR) ligand, transforming growth factor-α (TGF-α). We show that chronic (24 h) treatment with TGF-α inhibits ENaC in Xenopus laevis kidney cells 20 t...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692443/ https://ncbi.nlm.nih.gov/pubmed/19297452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90337.2008 |
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