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The inhibitory effect of G(βγ) and G(β) isoform specificity on ENaC activity
Epithelial Na(+) channel (ENaC) activity, which determines the rate of renal Na(+) reabsorption, can be regulated by G protein-coupled receptors. Regulation of ENaC by Gα-mediated downstream effectors has been studied extensively, but the effect of G(βγ) dimers on ENaC is unclear. A6 cells endogenou...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840225/ https://ncbi.nlm.nih.gov/pubmed/23863469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00009.2013 |
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