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Inhibition of αENaC expression and ENaC activity following blockade of the circadian clock-regulatory kinases CK1δ/ε

Increasing evidence suggests that the circadian clock plays an important role in the control of renal function and blood pressure. We previously showed that the circadian clock protein Period (Per)1, positively regulates the expression of the rate limiting subunit of the renal epithelial sodium chan...

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Autori principali: Richards, Jacob, Greenlee, Megan M., Jeffers, Lauren A., Cheng, Kit-Yan, Guo, Laijing, Eaton, Douglas C., Gumz, Michelle L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469687/
https://ncbi.nlm.nih.gov/pubmed/22832921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00678.2011
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