Direct Ras Inhibitors Identified from a Structurally Rigidified Bicyclic Peptide Library

A one-bead-two-compound (OBTC) library of structurally rigidified bicyclic peptides was chemically synthesized on TentaGel microbeads (90 μm), with each bead displaying a unique bicyclic peptide on its surface and a linear encoding peptide of the same sequence in its interior. Screening of the libra...

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Bibliographic Details
Main Authors:	Upadhyaya, Punit, Qian, Ziqing, Habir, Nurlaila A. A., Pei, Dehua
Format:	Artigo
Language:	Inglês
Published:	2014
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4180945/ https://ncbi.nlm.nih.gov/pubmed/25284901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2014.05.113
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Direct Ras Inhibitors Identified from a Structurally Rigidified Bicyclic Peptide Library

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