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Direct Ras Inhibitors Identified from a Structurally Rigidified Bicyclic Peptide Library
A one-bead-two-compound (OBTC) library of structurally rigidified bicyclic peptides was chemically synthesized on TentaGel microbeads (90 μm), with each bead displaying a unique bicyclic peptide on its surface and a linear encoding peptide of the same sequence in its interior. Screening of the libra...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180945/ https://ncbi.nlm.nih.gov/pubmed/25284901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2014.05.113 |
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