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DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the Zucker obese rat
OBJECTIVE: Obesity-related glomerulopathy is characterized initially by glomerular hyperfiltration with hypertrophy and then development of proteinuria. Putative mechanisms include endothelial dysfunction and filtration barrier injury due to oxidant stress and immune activation. There has been recen...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180797/ https://ncbi.nlm.nih.gov/pubmed/24995775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20833 |
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