DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the Zucker obese rat

OBJECTIVE: Obesity-related glomerulopathy is characterized initially by glomerular hyperfiltration with hypertrophy and then development of proteinuria. Putative mechanisms include endothelial dysfunction and filtration barrier injury due to oxidant stress and immune activation. There has been recen...

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Main Authors: Nistala, Ravi, Habibi, Javad, Aroor, Annayya, Sowers, James R, Hayden, Melvin R, Meuth, Alex, Knight, William, Hancock, Tamara, Klein, Thomas, DeMarco, Vincent G, Whaley-Connell, Adam
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180797/
https://ncbi.nlm.nih.gov/pubmed/24995775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20833
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