Dipeptidylpeptidase Inhibition Is Associated with Improvement in Blood Pressure and Diastolic Function in Insulin-Resistant Male Zucker Obese Rats

Diastolic dysfunction is a prognosticator for future cardiovascular events that demonstrates a strong correlation with obesity. Pharmacological inhibition of dipeptidylpeptidase-4 (DPP-4) to increase the bioavailability of glucagon-like peptide-1 is an emerging therapy for control of glycemia in typ...

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Autori principali: Aroor, Annayya R., Sowers, James R., Bender, Shawn B., Nistala, Ravi, Garro, Mona, Mugerfeld, Irina, Hayden, Melvin R., Johnson, Megan S., Salam, Muhammad, Whaley-Connell, Adam, DeMarco, Vincent G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2013
Soggetti:
Renal-Cardiac-Vascular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689282/
https://ncbi.nlm.nih.gov/pubmed/23653460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1096
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