Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice

Overnutrition/obesity predisposes individuals, particularly women, to diastolic dysfunction (DD), an independent predictor of future cardiovascular disease. We examined whether low-dose spironolactone (Sp) prevents DD associated with consumption of a Western Diet (WD) high in fat, fructose, and sucr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Bostick, Brian, Habibi, Javad, DeMarco, Vincent G., Jia, Guanghong, Domeier, Timothy L., Lambert, Michelle D., Aroor, Annayya R., Nistala, Ravi, Bender, Shawn B., Garro, Mona, Hayden, Melvin R., Ma, Lixin, Manrique, Camila, Sowers, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551127/
https://ncbi.nlm.nih.gov/pubmed/25747754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00898.2014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados