Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice

Overnutrition/obesity predisposes individuals, particularly women, to diastolic dysfunction (DD), an independent predictor of future cardiovascular disease. We examined whether low-dose spironolactone (Sp) prevents DD associated with consumption of a Western Diet (WD) high in fat, fructose, and sucr...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Heart Circ Physiol
Egile Nagusiak: Bostick, Brian, Habibi, Javad, DeMarco, Vincent G., Jia, Guanghong, Domeier, Timothy L., Lambert, Michelle D., Aroor, Annayya R., Nistala, Ravi, Bender, Shawn B., Garro, Mona, Hayden, Melvin R., Ma, Lixin, Manrique, Camila, Sowers, James R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2015
Gaiak:
Integrative Cardiovascular Physiology and Pathophysiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551127/
https://ncbi.nlm.nih.gov/pubmed/25747754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00898.2014
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