Low Dose Mineralocorticoid Receptor Blockade Prevents Western Diet-induced Arterial Stiffening in Female Mice

Women are especially predisposed to development of arterial stiffening secondary to obesity due to consumption of excessive calories. Enhanced activation of vascular mineralocorticoid receptors impairs insulin signaling, induces oxidative stress, inflammation and maladaptive immune responses. We tes...

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Foilsithe in:Hypertension
Main Authors: DeMarco, Vincent G., Habibi, Javad, Jia, Guanghong, Aroor, Annayya R., Ramirez, Francisco, Martinez-Lemus, Luis A., Bender, Shawn B., Garro, Mona, Hayden, Melvin R., Sun, Zhe, Meininger, Gerald A., Manrique, Camila, Whaley-Connell, Adam, Sowers, James R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465849/
https://ncbi.nlm.nih.gov/pubmed/26015449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05674
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