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Diet induced obesity promotes kidney endothelial stiffening and fibrosis dependent on the endothelial mineralocorticoid receptor

Obesity is characterized by enhanced mineralocorticoid receptor (MR) activation, vascular stiffness and associated cardiovascular and kidney disease. Consumption of a western style diet (WD), high in saturated fat and refined carbohydrates, by female mice, leads to obesity and vascular stiffening. U...

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Bibliografiske detaljer
Udgivet i:Hypertension
Main Authors: Aroor, Annayya R., Javad, Habibi, Nistala, Ravi, Ramirez-Perez, Francisco I., Martinez-Lemus, Luis A., Jaffe, Iris Z., Sowers, James R., Jia, Guanghong, Whaley-Connell, Adam
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448566/
https://ncbi.nlm.nih.gov/pubmed/30827147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12198
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