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Diet induced obesity promotes kidney endothelial stiffening and fibrosis dependent on the endothelial mineralocorticoid receptor

Obesity is characterized by enhanced mineralocorticoid receptor (MR) activation, vascular stiffness and associated cardiovascular and kidney disease. Consumption of a western style diet (WD), high in saturated fat and refined carbohydrates, by female mice, leads to obesity and vascular stiffening. U...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Aroor, Annayya R., Javad, Habibi, Nistala, Ravi, Ramirez-Perez, Francisco I., Martinez-Lemus, Luis A., Jaffe, Iris Z., Sowers, James R., Jia, Guanghong, Whaley-Connell, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448566/
https://ncbi.nlm.nih.gov/pubmed/30827147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12198
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