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Diet induced obesity promotes kidney endothelial stiffening and fibrosis dependent on the endothelial mineralocorticoid receptor
Obesity is characterized by enhanced mineralocorticoid receptor (MR) activation, vascular stiffness and associated cardiovascular and kidney disease. Consumption of a western style diet (WD), high in saturated fat and refined carbohydrates, by female mice, leads to obesity and vascular stiffening. U...
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| Veröffentlicht in: | Hypertension |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6448566/ https://ncbi.nlm.nih.gov/pubmed/30827147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12198 |
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