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Pleiotropic effects of the dipeptidylpeptidase-4 inhibitors on the cardiovascular system
Dipeptidylpeptidase-4 (DPP-4) is a ubiquitously expressed transmembrane protein that removes NH(2)-terminal dipeptides from various substrate hormones, chemokines, neuropeptides, and growth factors. Two known substrates of DPP-4 include the incretin hormones glucagon-like peptide-1 (GLP-1) and gastr...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137125/ https://ncbi.nlm.nih.gov/pubmed/24929856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00209.2014 |
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