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Sumo E2 Ligase UBC9 is Required for Efficient Protein Quality Control in Cardiomyocytes

RATIONALE: Impairment of proteasomal function is pathogenic in a number of cardiac proteinopathies and can eventually lead to heart failure. Loss of proteasomal activity often results in the accumulation of large protein aggregates. The ubiquitin proteasome system (UPS) is primarily responsible for...

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Detaylı Bibliyografya
Asıl Yazarlar: Gupta, Manish K., Gulick, James, Liu, Ruijie, Wang, Xuejun, Molkentin, Jeffery D., Robbins, Jeffrey
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180728/
https://ncbi.nlm.nih.gov/pubmed/25097219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.304760
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