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Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex.
The Small Ubiquitin-related Modifier SUMO-1 belongs to the ubiquitin (Ub) and ubiquitin-like (Ubl) protein family. SUMO conjugation occurs on specific lysine residues within protein targets, regulating pathways involved in differentiation, apoptosis, the cell cycle, and responses to stress by alteri...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1416492/ https://ncbi.nlm.nih.gov/pubmed/15931224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03588 |
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