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Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex.

The Small Ubiquitin-related Modifier SUMO-1 belongs to the ubiquitin (Ub) and ubiquitin-like (Ubl) protein family. SUMO conjugation occurs on specific lysine residues within protein targets, regulating pathways involved in differentiation, apoptosis, the cell cycle, and responses to stress by alteri...

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Bibliografiske detaljer
Main Authors: Reverter, David, Lima, Christopher D.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1416492/
https://ncbi.nlm.nih.gov/pubmed/15931224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03588
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