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Altered Activity in the Central Medial Thalamus Precedes Changes in the Neocortex during Transitions into Both Sleep and Propofol Anesthesia

How general anesthetics cause loss of consciousness is unknown. Some evidence points toward effects on the neocortex causing “top-down” inhibition, whereas other findings suggest that these drugs act via subcortical mechanisms, possibly selectively stimulating networks promoting natural sleep. To de...

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Detalhes bibliográficos
Main Authors: Baker, Rowan, Gent, Thomas C., Yang, Qianzi, Parker, Susan, Vyssotski, Alexei L., Wisden, William, Brickley, Stephen G., Franks, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180471/
https://ncbi.nlm.nih.gov/pubmed/25274812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1519-14.2014
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