GABAergic Inhibition of Histaminergic Neurons Regulates Active Waking But Not the Sleep–Wake Switch or Propofol-Induced Loss of Consciousness

The activity of histaminergic neurons in the tuberomammillary nucleus (TMN) of the hypothalamus correlates with an animal's behavioral state and maintains arousal. We examined how GABAergic inputs onto histaminergic neurons regulate this behavior. A prominent hypothesis, the “flip-flop” model,...

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Detalhes bibliográficos
Main Authors: Zecharia, Anna Y., Yu, Xiao, Götz, Thomas, Ye, Zhiwen, Carr, David R., Wulff, Peer, Bettler, Bernhard, Vyssotski, Alexei L., Brickley, Stephen G., Franks, Nicholas P., Wisden, William
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466043/
https://ncbi.nlm.nih.gov/pubmed/22993424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2931-12.2012
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