Altered Activity in the Central Medial Thalamus Precedes Changes in the Neocortex during Transitions into Both Sleep and Propofol Anesthesia

How general anesthetics cause loss of consciousness is unknown. Some evidence points toward effects on the neocortex causing “top-down” inhibition, whereas other findings suggest that these drugs act via subcortical mechanisms, possibly selectively stimulating networks promoting natural sleep. To de...

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Main Authors: Baker, Rowan, Gent, Thomas C., Yang, Qianzi, Parker, Susan, Vyssotski, Alexei L., Wisden, William, Brickley, Stephen G., Franks, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180471/
https://ncbi.nlm.nih.gov/pubmed/25274812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1519-14.2014
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