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Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

Genetic analysis of familial forms of Alzheimer's disease (AD) causally links the proteolytic processing of the amyloid precursor protein (APP) and AD. However, the specific type of amyloid and mechanisms of amyloid pathogenesis remain unclear. We conducted a detailed analysis of intracellular...

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Bibliographische Detailangaben
Hauptverfasser: Pensalfini, Anna, Albay, Ricardo, Rasool, Suhail, Wu, Jessica, Hatami, Asa, Arai, Hiromi, Margol, Lawrence, Milton, Saskia, Poon, Wayne, Corrada, Maria, Kawas, Claudia, Glabe, Charles
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179983/
https://ncbi.nlm.nih.gov/pubmed/25092575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.07.011
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