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Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

Genetic analysis of familial forms of Alzheimer's disease (AD) causally links the proteolytic processing of the amyloid precursor protein (APP) and AD. However, the specific type of amyloid and mechanisms of amyloid pathogenesis remain unclear. We conducted a detailed analysis of intracellular...

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Main Authors: Pensalfini, Anna, Albay, Ricardo, Rasool, Suhail, Wu, Jessica, Hatami, Asa, Arai, Hiromi, Margol, Lawrence, Milton, Saskia, Poon, Wayne, Corrada, Maria, Kawas, Claudia, Glabe, Charles
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179983/
https://ncbi.nlm.nih.gov/pubmed/25092575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.07.011
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