Novel Indole-2-Carboxamide Compounds Are Potent Broad-Spectrum Antivirals Active against Western Equine Encephalitis Virus In Vivo

Neurotropic alphaviruses, including western, eastern, and Venezuelan equine encephalitis viruses, cause serious and potentially fatal central nervous system infections in humans for which no currently approved therapies exist. We previously identified a series of thieno[3,2-b]pyrrole derivatives as...

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Autori principali: Delekta, Phillip C., Dobry, Craig J., Sindac, Janice A., Barraza, Scott J., Blakely, Pennelope K., Xiang, Jianming, Kirchhoff, Paul D., Keep, Richard F., Irani, David N., Larsen, Scott D., Miller, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178776/
https://ncbi.nlm.nih.gov/pubmed/25031353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01671-14
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