Novel Indole-2-Carboxamide Compounds Are Potent Broad-Spectrum Antivirals Active against Western Equine Encephalitis Virus In Vivo

Neurotropic alphaviruses, including western, eastern, and Venezuelan equine encephalitis viruses, cause serious and potentially fatal central nervous system infections in humans for which no currently approved therapies exist. We previously identified a series of thieno[3,2-b]pyrrole derivatives as...

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Detalhes bibliográficos
Main Authors: Delekta, Phillip C., Dobry, Craig J., Sindac, Janice A., Barraza, Scott J., Blakely, Pennelope K., Xiang, Jianming, Kirchhoff, Paul D., Keep, Richard F., Irani, David N., Larsen, Scott D., Miller, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178776/
https://ncbi.nlm.nih.gov/pubmed/25031353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01671-14
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