Discovery of Anthranilamides as a Novel Class of Inhibitors of Neurotropic Alphavirus Replication

Neurotropic alphaviruses are debilitating pathogens that infect the central nervous system (CNS) and are transmitted to humans via mosquitoes. There exist no effective human vaccines against these viruses, underlining the need for effective antivirals, but no antiviral drugs are available for treati...

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Pubblicato in:Bioorg Med Chem
Autori principali: Barraza, Scott J., Delekta, Philip C., Sindac, Janice A., Dobry, Craig J., Xiang, Jianming, Keep, Richard F., Miller, David J., Larsen, Scott D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363283/
https://ncbi.nlm.nih.gov/pubmed/25740634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.01.054
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