Discovery of Anthranilamides as a Novel Class of Inhibitors of Neurotropic Alphavirus Replication

Neurotropic alphaviruses are debilitating pathogens that infect the central nervous system (CNS) and are transmitted to humans via mosquitoes. There exist no effective human vaccines against these viruses, underlining the need for effective antivirals, but no antiviral drugs are available for treati...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Barraza, Scott J., Delekta, Philip C., Sindac, Janice A., Dobry, Craig J., Xiang, Jianming, Keep, Richard F., Miller, David J., Larsen, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363283/
https://ncbi.nlm.nih.gov/pubmed/25740634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.01.054
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