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Bclx regulates the survival of double-positive thymocytes.

The bclx gene has been shown to regulate programmed cell death in vitro. We now show that Bclx expression increases dramatically when T cells differentiate from CD4- CD8- (double negative) thymocytes to CD4+ CD8+ [double positive (DP)] thymocytes. In contrast single-positive (SP) thymocytes express...

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Autors principals: Ma, A, Pena, J C, Chang, B, Margosian, E, Davidson, L, Alt, F W, Thompson, C B
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC41787/
https://ncbi.nlm.nih.gov/pubmed/7761398
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