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Phorbol esters and CAMP differentially regulate the expression of CD4 and CD8 in human thymocytes

BACKGROUND: Intrathymic development and selection of the T lymphocyte repertoire is restricted by the interactions of the T cell antigen receptor and CD4 or CD8 co-receptors with self major histocompatibility complex molecules. Positive or negative selection depends on a tight regulatory control of...

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Autors principals: Martinez-Valdez, Hector, Madrid-Marina, Vicente, Cohen, Amos
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC65519/
https://ncbi.nlm.nih.gov/pubmed/11835689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-3-1
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