Precommitment of CD4+CD8+ thymocytes to either CD4 or CD8 lineages.
CD4+ and CD8+ mature T cells arise from CD4+CD8+ precursors in the thymus. During this process, cells expressing T-cell receptors (TCRs) reactive with self major histocompatibility complex (MHC) class I or II molecules are positively selected to the CD8 or CD4 lineage, respectively. It is controvers...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.19.8982 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|